A cross sectional study of patients knowledge and attitude towards the drug-drug interactions in Coimbatore district India

Arumugam Madeswaran, Abhijath M, Achsah R. B., Alka T


The current objective of this study was to assess the patient’s knowledge and attitudes toward the drug-drug interactions, a survey instrument included questions about the patient’s demographic information, familiarity with drug-drug interactions, usage of other system of medicines and the patient’s comfort level when discussing drug-drug interactions.76% believed that drugs won’t produce any interactions with other drugs. 58% of participants indicated that they were taken both allopathic and other system of medicines without the notification of physician. 64% of the respondents were stated that they were not able to communicate with the physician properly. The result of the current study reveals that the patients not having enough knowledge about drug-drug interactions and further indicates that the communication issue is a major factor for the drug-drug interactions. Hence the remedy suggested for reducing the drug-drug interactions are to enhance the time of counseling, and providing seminars, awareness, and programs regarding the need of effective communication and drug-drug interactions information to the overall population.


Allopathic drugs,Communication,Physician, Interactions

Full Text:



Merle L, Laroche ML, Dantoine T, Charmes JP. Predicting and Preventing Adverse Drug Reactions in the Very Old. Drugs and Aging 2005; 22 (5): 375-92.

Bailey DG, Malcolm J, Arnold O, Spence JD. Grapefruit juice-drug interactions. Br J Clin Pharmacol 1998; 46 (2): 101–10.

Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Lindau ST. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA 2008; 300 (24): 2867–78.

Haider SI, Johnell K, Thorslund M, Fastbom J. Trends in polypharmacy and potential drug-drug interactions across educational groups in elderly patients in Sweden for the period 1992–2002. Int J Clin Pharmacol Ther. 2007; 45(12): 643–53.

Haider SI, Johnell K, Weitoft GR, Thorslund M, Fastbom J. The influence of educational level on polypharmacy and inappropriate drug use: a register-based study of more than 600,000 older people. J Am Geriatr Soc. 2009; 57 (1): 62–9.

Ko Y, Malone DC, Skrepnek GH, Armstrong EP, Murphy JE, Abarca J, et al.Prescribers' knowledge of and sources of information for potential drug-drug interactions: a postal survey of US prescribers.Drug Saf. 2008; 31(6): 525-36.

Becker ML, Kallewaard M, Caspers PW, Schalekamp T, Stricker BH. Potential determinants of drug-drug interaction associated dispensing in community pharmacies. Drug Saf 2005; 28:371-8.

Rosholm JU, Bjerrum L, Hallas J, Worm J, Gram LF. Polypharmacy and the risk of drug-drug interactions among Danish elderly-A prescription database study. Dan Med Bull 1998; 45:210–3.

Hansten PD. Drug interaction management. Pharm World Sci 2003; 25: 94–7.

Madeswaran A, Venkateswaramurthy N. Herb-drug interactions: A survey of use, attitudes and knowledge among patients.Inventi Impact: Pharmacy Practice2012; 177: 1-5.

Madeswaran A, Dona K, Feroz SS, Fremil J. A Cross Sectional Study of Patients Attitude Towards the Knowledge and Rational Use of Antibiotics in South India. Inventi Rapid: Pharmacy Practice2015; 2015(2):1-3.

Murphy JE, Forrey RA, Desiraju U. Community pharmacists’ responses to drug-drug interaction alerts. Am J Health Syst Pharm 2004; 61:1484-7.

Indermitte J, Erba L, Beutler M, Bruppacher R, Haefeli WE, Hersberger KE. Management of potential drug interactions in community pharmacies: a questionnaire-based survey in Switzerland. Eur J Clin Pharmacol 2007; 63:297–305.

DOI: http://dx.doi.org/10.7439/ijasr.v1i2.1797

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM


  • There are currently no refbacks.

Copyright (c) 2015 International Journal of Advances in Scientific Research

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.