A Clinical Study of Oral Malignancies in Rural Set Up

Yashwant L. Durge, Megha A. Kawale, Vijay Potey

Abstract


Aim and Objectives: Aim of the present research was to study the epidemiologic profile, risk factors, different surgical approaches, post operative complications and surgical outcome of oral cancer in rural set up.

Methods: We conducted a clinical study of 30 histopathologically confirmed cases of oral cancer in tertiary care hospital, over a period of 23 months from December 2012 to October 2014. Data were collected and analyzed using SPSS computer software version 17.0 and Graph Pad Prism 5.0.

Results: Mean age of the patients was 55.46 years, ranging from 32-80 years; malignancy of oral cavity was common in males (60%) with a male: female ratio of 3:2. 20 (66.66%) oral cancer patients had risk habits, 33.33% were habituated for tobacco chewing and 20% for smoking and alcohol, moreover 6.67% were having addiction of smoking, alcohol and tobacco chewing and 6.67% were having addiction of smoking. Buccal mucosa was the commonest site of lesions (50%) followed by tongue (30%) and then lips (13.33). Wide local excision with modified radical neck dissection (50%) was most common surgical procedure done, followed by Hemiglossectomy with modified radical neck dissection (26.67%). Stitch infection was common early post operative complication while marginal flap necrosis was most common complication after reconstruction with PMMC flap. During follow up, 2 patient died mortality of patient was due to poor general condition and old age.

Conclusion: The malignancy of oral cavity was higher among elderly males predominantly with risk habits of tobacco consumption, also with increasing incidence in females. A surgical excision with wide margins and appropriate reconstruction is necessary to optimize the disease and functional outcome.


Keywords


Epidemiologic profile, Risk factors, Histopathology, Hemiglossectomy, PMMC flap

Full Text:

PDF

References


Petersen PE. Strengthening the prevention of oral cancer: the WHO perspective. Community Dentistry Oral Epidemiology 2005;33:397-399.

Ahluwalia H, Gupta S.C., Singh M, Mishra V, Singh P.A., Walia D.K. Spectrum of Head and Neck Malignancies in Allahabad. Indian Journal of Otolaryngology and Head and Neck Surgery , January - March 2001;53(1):16-21.

Elango JK, Gangadharan P, Sumithra S, and Kuriakose MA. Trends of head and neck cancers in urban and rural India. Asian Pacific Journal of Cancer Prevention, vol. 7

Anil K. Chaturvedi, William F. Anderson, Joannie Lortet-Tieulent, Maria Paula Curado, Jacques Ferlay, Silvia Franceschi, Philip S. Rosenberg, Freddie Bray, and Maura L. Gillison, "Worldwide Trends in Incidence Rates for Oral Cavity and Oropharyngeal Cancers"

PLopez Jornet, FJ Gomez Garcia, M Lucero Berdugo, F Parra Perez. A Pons-Fuster Lopez, "Mouth self-examination in a population at risk of oral cancer"

Wen-Jiun Lin, Rong-San Jiang, Shang-Heng Wu, Fun-Jou Chen, and Shih-An Liu "Smoking, Alcohol, and Betel Quid and Oral Cancer: A Prospective Cohort Study"

Sankaranarayanan R, Ramadas K, Thomas G et.al. Effects Of Screening On Oral Cancer Mortality In Kerala, India: A Cluster Randamized Controlled Trial, The Lancet.2005;365(9475):1927-1933.

Manoharan N, Tyagi BB, Raina V. Cancer incidences in rural Delhi -2004-2005. Asian pacific journal of cancer prevention. 2010;11(1):73-78.

Khandekar SP, Bagdey PS, Tiwari RR. Oral cancer and some epidemiological factors: a hospital based study. Indian Journal of Community Medicine. July-September 2006; 31(3):157-159.

Kumar S, Hellar RF, Pandey U, Tewari V. et.al. Delay In Presentation Of Oral Cancer: A Multifactor Analytic Study Nation Medical Journal Of India. 2001;14(1):13-17.

Takácsi-Nagy Z, Oberna F, Somogyi A, Polgár Cs, Major T, Németh Gy: Experiences in the treatment of tumour of base of the tongue with high dose rate interstitial radiotherapy on the basis of a retrospective analysis Magyar Onkológia. 2000; 44: 117-121.

Balaram P, Sridhar H, Rajkumar T, Vaccarella S, Herrero R, Nandakumar A, et al. Oral cancer in Southern India: The influence of smoking, drinking, pan chewing and oral hygiene. Int J Cancer 2002;98:440-445.

Patel MM and Pandya AN. Relationship of oral cancer with age, sex, site distribution and habits. Indian J Pathol Microbiol 2004; 47(2): 195-197.

Bhattacharjee A, Chakraborty A, Purkaystha P. Prevalence of head and neck cancers in North East – An institutional study. Indian J Otolaryngol Head Neck Surg 2006; 58(1): 15-19.

Abhinandan B, Chakraborty A, Purkaystha P. Prevalence of head and neck cancers in the North East-An institutional study. Indian J Otolaryngol Head Neck Surg 2006;58:15-19.

Ahluwalia H, Gupta SC, Singh M, Gupta SC, Mishra V, Singh PA, et al. Spectrum of Head -Neck cancers at Allahabad. Indian J Otolaryngol Head Neck Surg 2001;53(1):16-21.

Durazzo MD, Araujo CEN, Neto JSB, Potenza AS, Costa Pedro, Takeda F et al. clinical and epidemiological features of oral cancer ina medical school teaching hospital from 1994 to 2002: increasing incidence in women, predominance of advanced local disease, and low incidence of neck metastases.CLINICS 2005;60(4)293-298.

Mehrotra R, Singh M, Kumar D, Pandey AN, Gupta RK, Sinha US. Age specific incidence rate and pathological spectrum of oral cancer in Allahabad. Indian J Med Sci 2003; 57 (9): 400-4.

Muwonge R, Ramadas K, Sankila R, Thara S, Thomas G, Vinoda J, et al. Role of tobacco smoking, chewing and alcohol drinking in the risk of oral cancer in Trivandrum, india: A nested case-control design using incident cancer cases. Oral oncol 2008;44: 446-454.

More Y, D’cruz A. Oral cancer: Review of current management strategies. Natl Med J India. 2013;26(3):152-8.

Bhat SP, Naik R, Swetadri DK, D‘souza H Jayprakash CS, Bhat V. Clinicopathological Spectrum of Malignancies Of Oral cavity And Oropharynx-Our Experience In Referral Hospital World Articles In ENT.2010;3(1).

Jashvanth G, Murali K, Kasa S, Ramesh K. A Study on Clinical Presentations of Oral Cancer at Tertiary Care Hospital, Bellary, Karnataka. IJSR 2014;3(7):234.

Malhotra A et al. Demographic,Histopathological Patterns and Clinical profile of Oral Squamous Cell Carcinoma (OSCC) at a tertiary level referral Hospital in Vidarbha ( Central India) : A 7-year Retrospective Study. Nov 2014;13(II):53-56.

Rana M et al. Modern surgical management of tongue carcinoma-A clinical retrospective research over a 12 years period.Head and neck oncology 2011;3;43.

Moretti A, Vitullo F, Augurio A, et.al. Surgical Management Of Lip Cancer. Acta Otorhinolaryngol Ital. 2011;31:5-10.

Lekawale H, Patil B. Pectoralis Major Myocutaneous Flap for Oral Cavity Cancer Reconstruction - Our Experience with 30 Cases. Ind Journ of Appl Resear 2012;2(3) :159-161.




DOI: http://dx.doi.org/10.7439/ijbar.v8i3.4050

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 International Journal of Biomedical and Advance Research

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.