Variations serum electrolyte level during different phases of menstrual cycle in healthy female medical students

Abhilasha Mishra, R. B. Kamal

Abstract


Introduction- The menstrual cycle is characterized by cyclical fluctuations in the levels of FSH, LH, estrogen and progesterone. But the changes occur in serum electrolyte level have not been clearly established.

Objective- To compare the serum electrolyte level in different phases of menstrual cycle.

Material and method- The present study was carried out on 54 healthy female medical students in the age group of 18 to 24 years with normal menstrual cycle of 27-33 days. Serum electrolytes like, calcium, sodium and potassium, were estimated during menstrual, Proliferative and Secretory phases of menstrual cycle using standard procedures.

Results- There was a significant changes in the level of serum calcium during proliferative phase, sodium is increased maximally during menstrual phase and  potassium in secretory phase of menstrual cycle.

Conclusion- Alternation of serum  calcium, serum sodium and Potassium levels were noted during uterine changes of menstrual cycle, however, none of all the mention levels were outside the physiological limits.


Keywords


menstrual cycle, calcium, sodium, potassium, progesterone, estrogen, menstrual phase, proliferative phase, secretory phase.

Full Text:

PDF

References


Strassmann BI.The evolution of endometrial cycles and menstruation. Q Rev Biol 1996; 71 (2): 181–220.

A. J. Hsch , E. J. Peck, J. H. Clark. Progesterone antagonism of estrogen receptor and estrogen induced growth. Nature. 1975;254:337–339.

C. Christiansen, B. J. Riss. Five years with continuous combined estrogen progesterone therapy: Effect on calcium metabolism, lipoproteins and bleeding pattern. Br J Obstet Gynaecol. 1990;97:1087–92.

Halbreich U. Psychoneuroendocrinology 2003; 28 Suppl 3:55-99

Angat J, Sellaro R, Merikangas KR, Enicott J. Acta Pyschiatr Scand 2001; 104: 110-6.

Dickerson, Lori M, Mazyck, Pamela J,Hunter, Melissa H. American Family Physician 2003; 67 (8): 1743-52.

Matlin, Margaret W. The Psychology of Women. Sixth Edition 2008;

Amy Scholten, MPH. What are the risk factors for premenstrual syndrome?. Premenstrual Syndrome, Harvard Medical school: 2008;01-10.

Leon S, Robert H, Nathan G. Clinical Gynecologic Endocrinocology and Infertitility,4th Edn, William and Willkins publication; pp- 132.

. Frank RHT. The hormonal causes of premenstrual tension. Arch Neurol Psychiatry. 1931; 26: 1053-1057.

. M. L. Forsling, M. Akerlund, P. Stromberg. Variations in plasma concentrations of vasopresain during the menstrual cycle. J Endocrinol. 1981; 89,263-266.

. R. L. Landau, K. Lugibihl. Inhibition of the sodium-retaining influence of aldosterone by progesterone. J Clin Endocrinol Metab.1958; 18:1237-1245.

. Hak AE, Choi HK. Menopause, postmenopausal hormone use and serum uric acid levels in US women – The Third National Health and Nutrition Examination Survey. Arthritis Res Ther 2008; 10(5):R116.

. Christiansen C, Riss BJ. Five years with continuous combined estrogen progesterone therapy: Effect on calcium metabolism, lipoproteins and bleeding pattern. Br J Obstet Gynaecol 1990; 97:1087-92.

. Guyton AC, Hall JE. Textbook of medical physiology. 9 th ed. Bangalore: W.B. Saunders Company, Prism Book Pvt. Ltd. 1994; p. 992-993.

Das B, Chandra MP ,SamantaS, Mallick AK, Sowmya M.K, SERUM INORGANIC PHOSPHORUS, URIC ACID, CALCIUM, MAGNESIUM AND SODIUM STATUS DURING UTERINE CHANGES OF MENSTRUAL CYCLE,IJBR 3[04] [2012]209‐213.

. Christiansen C, Riss BJ, Rodro P. Prediction of rapid bone loss in postmenopausal women. Lancet 1987 May 16; 1(8542):1105-8.

A. K. Pandya, S. Chandwani, T. K. Das et al. Serum calcium, magnesium and inorganic phosphorus levels during various phases of menstrual cycle. Indian J Physiol Pharmacol. 1995;39:411–4.

P. Dullo, N. Vedi. Changes in serum calcium, magnesium and inorganic phosphorus levels during different phases of the menstrual cycle. J Hum Reprod Sci. 2008;1(2):77-80.

A. Mauskop, B. T. Altura, R. Q. Cracco, et al. An open trial of magnesium supplementation for the treatment of migraines and symptoms of premenstrual syndromes in premenopausal women: Effect on serum ionized magnesium level. Neurology. 1997;48:A261–2.

E. R. Bertone-Johnson, P.O. Chocano-Bedoya, S. E. Zagarins, et al. Dietary vitamin D intake, 25-hydroxyvitamin D3 levels and premenstrual syndrome in a college-aged population. J Steroid Biochem Mol Biol. 2010;121(1-2):434-7.

Malipatil BS, and Shilpa Patil,2013 Serum Electrolyte Status and Liver Functions in Different Phases of Menstrual Cycle , RJPBCS Volume 4 Issue 2,989-996.

Tsai PS, Yucha CB, Sheffield D and Yang, M. Clin Sci 1991; 81(4): 515-8.

AK Pandya, S Chandwani, TK Das et al. Indian J Physiol Pharmacol 1995; 39: 411-4.

D. S. Janowsky, J. L. Rausch, J. M. Davis. Historical studies of premenstrual tension up to 30 years ago: implications for future research. Curr Psychiatry Rep. 2002;4(6):411-8.




DOI: http://dx.doi.org/10.7439/ijbr.v6i7.2285

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM

Refbacks

  • There are currently no refbacks.




Copyright (c) 2015 International Journal of Biomedical Research

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.