Coccidian parasitic infection in HIV positive patients attending Tertiary care Hospital in Nepal

Rinku Sah, Rajendra Gurung, Nimesh Poudyal, Ratna Baral, Suman Rijal, Shyamal Kumar Bhattacharya

Abstract


Abstract:

Background: Enteric opportunistic parasites are the leading cause of gastrointestinal tract infection in patients with HIV/AIDS. This study was carried out to establish the occurrence of intestinal coccidian parasitic infection among the HIV positive patients in Eastern Nepal.

Materials and method:  This was a hospital based study carried out in Microbiology laboratory, BPKIHS, Dharan, Nepal over a period of one year (May 2013 to April 2014). All HIV positive patients with CD4+ count ≤200cells/µl were included. Total 50 HIV positive patients participated in the study over one year period.  Stool sample was collected after taking an informed written consent from the patient. Isolation and identification was done as per standard Microbiological procedure.

Result:. The overall prevalence of intestinal parasitic infection in present study was 38%. Among the parasites, coccidian parasites comprised of 57.89% of total parasitosis, among 20% (n= 10) cases. Out of total coccidian parasites identified Cryptosporidium parvum comprised 72.7%, Cyclospora cayetanensis 18.2% and Isospora belli 9.1%. One patient had mixed Cryptosporidial and Cyclospora infection.

 

Conclusion Coccidian parasitic infections are common in HIV positive patients at lower CD4+ count in Eastern part of Nepal.

 

Key words: HIV, opportunistic infections, coccidian parasite

 

 

 


Keywords


HIV, opportunistic infections, coccidian parasite

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References


References:

Global report: UNAIDS report on the global AIDS epidemic 2013. Geneva, UNAIDS.

Amatya R, Shrestha R, Poudyal N, Bhandari S. Opportunistic intestinal parasites and CD4+ count in HIV infected people. J Path Nepal 2011; 1: 118-21.

Vyas N, Pathan N, Aziz A. Enteric pathogens in HIV-positive patients with diarrhea and their correlation with CD4+ T-lymphocyte counts. Trop Parasitol 2012; 2:29-34.

Parmer R, Sharma V, Thakkar C, Chaudhary A, Pateliya U, Ninama G, et al. Prevalence of opportunistic fungal infections in HIV positive patients in tertiary care hospital in Rajkot. National J Med Res 2012; 2:463-5.

Kulkarni SV, Kairon R, Sane SS et al. Oppurtunistic parasitic infections in HIV/AIDS patients presenting with diarrhoea by the level of immunosuppression. Indian J Med Res 2009; 130:63-6.

Zhu J, Paul WE. CD 4 T-cells:fates, function and faults. Blood 2008; 112: 1557-69.

Vinay KV, Sandeep GN, Vishal K, Beena DN. Study of the relationship between CD4+ count and clinical features in HIV-infected patients in South Indian population. Indian J Fundamental App Life Sci 2012; 2:153-61.

Damtie D, Yismaw G, Woldeyohannes D, Anagaw B. Common opportunistic infections and their CD4 cell correlates among HIV-infected patients attending at antiretroviral therapy clinic of Gondar University Hospital, Northwest Ethiopia. BMC Res 2013; 6:534.

WHO. Basic laboratory methods in medical parasitology. 1991: 9-18.

Sherchan JB, Ohara H, Sakurada S, Basnet A, Tandukar S, Bam D S. Enteric opportunistic parasitic infections anomg HIV-seropositive patients in Kathmandu, Nepal. Kathmandu Univ Med J 2012; 38: 14-7.

Gupta S, Narang S, Nuvanath V, Singh S. Chronic diarrhea in HIV patients; prevalence of coccidian parasites. Indian J Med Microbiol 2008; 26: 172-5.

Dhungel BA, Dhungel KU, Easow JM, Singh YI. Opportunistic infection among HIV seropositive cases in Manipal Teaching Hospital, Pokhara, Nepal. Kathm Uni Med J 2008; 6: 335-9.

Tiwari BR, Ghimire P, Malla S, Sharma B, Karki S. Intestinal parasitic infection among the HIV-infected patients in Nepal. J Infect Dev Ctries 2013; 7: 550-5.

Kumar SS, Ananthan S, Lakshmi P. Intestinal parasitic infection in HIV infected patients with diarrhoea in Chennai. Indian J Of Med Microbiol 2002; 20 (2): 88-91.




DOI: http://dx.doi.org/10.7439/ijbr.v8i7.4300

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