Fine needle aspiration cytology versus trucut biopsy in the diagnosis of breast cancer- A comparative study

Shashirekha C. A., Rahul Singh R., Ravikiran H. R., Krishna Prasad, Sreeramulu P. N.

Abstract


Background: Most diseases of the breast present as a palpable mass. The majority of breast lesions are not malignant, and most benign lesions do not progress to cancer; however the accuracy of diagnosis can be increased by a combination of preoperative tests like physical examination, mammography, fine-needle aspiration cytology (FNAC), and Tru cut needle biopsy (TGNB) or core needle biopsy (CNB). FNAC has grown in popularity and became the first initial used procedure after history taking and clinical examination for diagnosis of solid and cystic breast lumps. This study was designated to investigate the accuracy of FNAC in comparison to TCNB for diagnosis of breast masses.

Design: Retrospective Study 

Materials &Methods: In this study, 62 patients having breast lumps were studied during the period from January 2014 to January 2017 in terms of FNAC and Trucut Biopsy and were compared with tissue diagnosis. Variables like age, marital status, duration, size, menstrual status & site were analyzed using statistical analysis.

Results: Out of 62 patients with breast lump, 32 were diagnosed with Benign Breast lesions, and 30 with malignant lesions. Sensitivity of FNAC and TRUCUT biopsy were 84.34% and 97.1% respectively. TRUCUT was more accurate when compared to FNAC.


Keywords


FNAC, trucut biopsy, breast lump, mammography, malignancy, tissue diagnosis

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References


. Masood S, Frykberg ER, Mclellan GL et al. Prospective evaluation of radiologically directed fine- needle aspiration biopsy of non palpable breast lesions. Cancer 1990; 66:1480-7.

. Eman Muhammad et al. validity of fine needle aspiration cytology in diagnosis of breast lumps in upper Egypt, J. Med. Lab. Sci., 2012; 21(1): 69-81.

. Patel, J.J., Gartell, P.C., Smallwood, J.A. et al. Fine needle aspiration cytology of breast masses: an evaluation of its accuracy and reasons for diagnostic failure. Ann R Coll Surg Engl. 1987; 69: 156–159.

. Joulaee A, Kalantari M, Kadivar M, Joulaee S, Bahrani N, Mangual M, Hosseini S, Gh. Etemadmoghadam G. Trucut biopsy of breast lesions: The first step toward international standards in developing countries. European Journal of Cancer 2012; 48:648– 654.

. Willems S M, Deurzen C H M van, Diest P J van. Diagnosis of breast lesions: fine-needle aspiration cytology or core needle biopsy? A review. Group.bmj.com 2011Oct 29.

. Farzana Memom, Sajida Qureshi. Sensitivity of fine needle aspiration vs. core biopsy in the diagnosis of palpable and clinically suspicious breast lesions. Pakistan Journal of Surgery 2009; 25 (3): 214-217.

. Bukhari M H, Arshad M, Jamal Shahid. Use of fine-needle aspiration in the evaluation of breast lumps. Pathology Research International. 2011 Article ID 689521, 10 pages.

. Pinder SE, Elston CW, Ellis IO. The role of preoperative diagnosis in breast cancer. Histopathology 1996; 28:563-6.




DOI: http://dx.doi.org/10.7439/ijbr.v8i9.4329

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