The study of association of serum parathyroid hormone level with obesity in subjects admitted to a tertiary care centre

Vishnu K, Indumathi Shankaraiah, Harishkiran N.E


Objectives: Obesity has become an ever growing problem of epidemic proportions. Recent researches in this field suggested a possible association of high serum parathyroid hormone level and low vitamin D level with obesity and metabolic syndrome. This study was conducted in Mysore Medical College, Mysore to evaluate association of obesity with high serum PTH level in obese individuals.

Methods: The study was conducted on 100 obese subjects admitted to medical wards who met the required criteria. Subjects were divided into different categories based on anthropometric measurements. Serum parathyroid hormone level was estimated in each group based on early morning sample drawn.

Results: Among 100 subjects studied, 52 were females and 48 were males. Subjects with grade 1 obesity had mean S.PTH value of 54.5pg/ml which was within normal population limit (8.9-82.4). Mean serum PTH in subjects of grade 2 obesity was 77.305, towards the upper limit of normal level (fourth quartile). Among patients with grade 3 obesity, serum PTH level was high with a mean value of 116.42 pg/ml. Pearson’s coefficient of analysis for association of S.PTH with waist circumference was 0.652 (less than 1). There was significant positive correlation for level of S.PTH with waist hip ratio (coefficient of correlation 0.530) These findings were statistically significant with a P value < 0.001.

Conclusion: The study shows that there is a significant association of high serum parathyroid hormone level with BMI. This association was most significant among subjects with morbid obesity. Analysis based on waist circumference and waist hip ratio also showed a positive correlation.


Body mass index (BMI), Serum parathyroid hormone (PTH), waist hip ratio, waist circumference.

Full Text:



Barness LA, Opitz JM, Gilbert-Barness E. "Obesity: genetic, molecular, and environmental aspects". American Journal of Medical Genetics December 2007 143A : 301634.

Haslam DW, James WP . "Obesity". Lancet(Review) 2005 366 : 1197209

Tsigos C, Hainer V, Basdevant A, Finer N, Fried M, Mathus-Vliegen E, Micic D,Maislos M, Roman G, Schutz Y, Toplak H, Zahorska-MarkiewiczB."Management of Obesity in Adults: European Clinical Practice Guidelines" (PDF). The European Journal of Obesity April 2008 1 (2): 10616.

Haslam D. "Obesity: a medical history".Obes Rev (Review). 8 Suppl March2007 1: 316


Monika Gupta, K. Prabhu, Prevalence of Diabetes Mellitus in South India retrospective Analysis. JIMSA October-December 2012 Vol. 25 No. 4

Kamycheva E, Sundsfjord J, Jorde R. Serum parathyroid hormone level is associated with body mass index. The 5th Troms study. Eur J Endocrinology. 2004 Aug;151(2):167-72.

Gareth Williams et al, Obesity- Science to Practice, Wiley Blackwell, 2009,

William osler . The Principles and Practice of Medicine 1905 : 1849-1929

Ancel Keys Journal of Chronic Diseases 1972 : 6-19



  • There are currently no refbacks.

Copyright (c) 2018 International Journal of Biomedical Research

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.