Screening of phyto-chemical constituents, trace metals and antimicrobial efficiency of Cissus vitiginea

V. Subramani, M. Kamaraj, B. Ramachandran, J. Jerome Jeyakumar

Abstract


The present study focused on the phytochemical constituents, antimicrobial activity and trace metal concentrations of the Cissus vitiginea plant leaves which were collected from the Tiruchirappalli district, southern India. Preliminary phytochemical screening of leaves extracts revealed the presence of the bioactive compounds, such as steroids, triterpenoids, glycosides, sugar, alkaloids, flavonoids, tannins, amino acid, and coumarin in the leaves. The bacterial and fungal strains were tested for antimicrobial sensitivity against C. vitiginea using the disc diffusion method. The methanol extracts of the plant leaves exhibited the higher zone of inhibition against bacterial strains than fungal strains. The trace metal concentrations were analyzed form the powered plant leaves by 797 VA Computrace voltametry, Metrohm. The average concentrations of Cd, Cr, Cu, Fe, Ni, Pb and Zn were 0.05, BDL, 018, 0.38, BDL, BDL and 0.48 mg kg-1, respectively. The bioactive compounds responsible for these antimicrobial activities could be isolated and identified to develop a new drug of pharmaceutical interest.


Keywords


Cissus vitiginea, Antimicrobial activity, Phytochemistry, Trace metals

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DOI: http://dx.doi.org/10.7439/ijpp.v4i3.103

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