Comparison on hypoglycemic effect of Oyster (Pleurotusosteratus) and Reishi (Ganodermalucidum) mushroom in alloxan induced diabetic mice

Debendra Nath Roy, A. K. Azad, Rokshana Sharmin, A. S.M. Anisuzzaman, Proma Khondkar

Abstract


Pleurotusosteratus (family: Pleurotaceae) and Ganodermalucidum (family: ganodermataceae) are common edible mushrooms in Bangladesh. Ethyl acetate extract of Pleurotusosteratus and Ganodermalucidum were used to find out their hypoglycaemicactivity in alloxan induced diabetic mice. Ethyl acetate extract of Pleurotusosteratus and Ganodermalucidum reduced blood glucose level of 39.56% and 43.27% respectively at 24 hours after intrapertitoneal administration (P<0.005) inalloxan induced diabeticmice.The possible mechanism of hypoglycemic action is due to the increased glucose uptake in liver cells because it markedly lowers the blood glucose levels in alloxan induced diabeticmice.


Keywords


hypoglycaemic; Alloxan induced diabetic mice; blood glucose; liver cell

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DOI: http://dx.doi.org/10.7439/ijpp.v5i3.2123

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