Top 5 Best Nootropic Supplements In 2023 – Natural Brain Boosting Formula!


So far, 2023 has been an astounding year as breakthroughs keep emerging especially in the health sector. Today, I will be sharing with you the top 5 best nootropic supplements of the year, 2023. Being nootropic means the five dietary supplements help in supporting mental functions.

Each of these five memory supports is claimed to be in high demand on the market today owing to their natural ingredients which perfectly combine to support mental clarity, enhance stress reduction, improve long-term memory, and stimulate attention span.

The formulas are said to be safe for consumption with zero side effects. Keep reading to know more about these best nootropic supplements of the year.

Top 5 Best Nootropic Supplements In 2023 – Tested And Reviewed!

In this article, we will be introducing the 5 Best Nootropic Supplements that we have shortlisted based on their results and benefits. 

  • Mind Lab Pro
  • Noocube
  • Nooceptin
  • Neurodrine
  • Vyvamind
Top 5 Best Nootropic Supplements

Designed to enhance cognitive functions these brain-boosting supplements are said to be made under sterile conditions using FDA-approved and GMP-certified facilities. The plants and herbs making up each of these dietary formulas seem to have been homogeneously blended and lab-tested for quality assurance and safety.

The nootropic pills are toxin-free and can be taken by any adult who loves to perform better at work, make good grades in school, or be proficient in business dealings. 

According to research, more than 6 million Americans are living with Alzheimer’s and other memory-related issues in 2023. Hence, the formulation of these top best formulas helps to correct such anomalies and restore mental sanity.

It is imperative to conduct reviews of these top 5 best nootropic supplements to verify their authenticity. That said, the benefits, ingredients, pros and cons, pricing, and refund policy shall be reviewed. Their rating factors will also be considered before concluding the analysis. Let’s get started. 

1. Mind Lab Pro

Mind Lab Pro

Mind Lab Pro is believed to be the world’s first universal nootropic formula. Designed in 2015, the dietary supplement seems to be raging on the market now as it’s known to improve brain functions by targeting multiple brain pathways such as brain energy and brain regeneration.

It is made of 11 research-based nootropics. According to the manufacturing team, the formula is made into capsules that are non-GMO using FDA-approved and GMP-certified facilities. Mind Lab Pro is said to be caffeine-free. It is backed with a 100% money-back guarantee. 

Mind Lab Pro Ingredients List

The Mind Lab Pro ingredients include Vitamin B6, Vitamin B9, Vitamin B12, Citicoline, Bacopa monnieri, N-Acetyl, L-Tyrosine, L-Theanine, Organic Lion’s Mane Mushroom, 24% Bacopa. 

Citicoline 250 mgIt boosts brain cell formation by 26% and brain energy by 13.6%, as shown in human research to promote mood balance, memory, focus, and attention.
Organic Lion’s Mane MushroomThe mushroom supports brain health. It supplies nootropics called hericenones and erinacines. When optimized, its nerve growth factor could stimulate new learning and memory. 
Rhodiola RoseaUsed for mental processing enhancement, memory, attention span, mood, and work capacity. Also for brain energy support and mental and physical stress strengthening
L-TyrosineThis amino acid enhances mental performance. According to research, L-Tyrosine may counter brain stress impact, helping in the synthesis of neurotransmitters depleted by high-pressure thinking. 
Bacopa monnieriFor enhancement of delayed recall memory, immediate recall memory, and in clinical research. According to research, Bacopa may induce mental processing and cognition optimization under stress. It could also promote relaxation. 

Benefits Offered By Mind Lab Pro

The following benefits come with using Mind Lab Pro:

Mental PerformanceAlmost all the ingredients used in Mind Lab Pro are found to increase mental performance such as learning processes, attention span, focus, and memory retention.
Mood BalanceMind Lab Pro helps in mood balance. Take Citicoline, which has been shown in human research to promote mood balance aside from its brain repair functions. 
Increase in Brain Energy Metabolism It helps the brain to break down its sugar for brain glucose formation and brain activity increase.
Age-Defying FunctionsThe ingredients are capable of maintaining healthy brain function against age-related changes and mental decline. 

Pros And Cons


  • Scientifically proven by renowned universities.
  • Non-GMO.
  • Research-backed ingredients used.
  • Clean label. 
  • GMP-certified and FDA-registered facilities.  
  • Caffeine-free. 


  • Seems a little too pricey.
  • All packages are not evenly discounted. 

Mind Lab Pro Pricing Plans

The following prices are available for Mind Lab Pro purchase.

  • 1 bottle (1-Month Supply) + 2.30/standard serving = ($69)
  • 2 bottles (2-Month Supply) + $2.30 standard serving + Fast Shipping = ($138)
  • 3 bottles (3-Month Supply) + 1 Free Bottle + 25% saving + $1.73 standard serving + Free Shipping = ($207)

If you are not pleased with your result after 30 days, call customer support for a 100% money-back guarantee. 

2. Noocube 


Noocube’s Brain Productivity is a 2023 brain dietary supplement formulated by a team of German researchers. It is made with an equal combination of natural ingredients rich in carotenoids which support memory molecules known as Brain-Derived Neurotrophic Factor (BDNF)

According to research, being overwhelmed is caused by stress on the brain’s prefrontal cortex. Uncontrollable stress could cause a loss of prefrontal cognitive abilities. Hence, the production of Noocube for cognitive health support especially at the cellular levels for memory, focus, and concentration. The pills seem to attract a lot of reviews and are supported by a refund policy. 

Noocube Ingredients List

The following are the ingredients used. 

Lutemax® 2020Naturally from the Marigold, Lutemax 2020 uses its nutrients, lutein, and zeaxanthin isomers (RS- and RR) zeaxanthin to protect the brain areas responsible for memory and vision alertness. When tested against a placebo, the results were improved attention span, boosted memory, reduced mental stress, and increased processing speed. 
Astragalus ExtractExtracted from the root of a traditional Chinese herb, EA protects induced learning, impairs memory, and increases neurocyte survival. It could decrease the apoptosis rate. 
Oat StrawThis ingredient has been active since the Middle Ages. Found in Northern Europe and some parts of North America, Oat Straw helps in stress and anxiety reduction. Also renowned for memory boost, attention span, and concentration.   
L-TyrosineA case study involving 22 women given a demanding task showed that the women with L-Tyrosine focused more (their concentration and memory improved) than those with placebo. 

Benefits Offered By Noocube

Sharp Focus Noocube is made with natural ingredients loaded with nutrients that are capable of enhancing focus and attention thereby helping you finish a set task. 
Memory and Mental Alertness Boost The natural ingredient blend works in synergy to support brain pathways consequently leading to mental alertness and problem-solving ability. 
Debilitating Brain Fog Reduction This formula is apt in reversing the inability to remember events, leaving you with cognitive function and recollection ability
Eye Protection One of the ingredients used in Noocube formation, Lutemax® 2020 contains three critical eye-brain nutrients, lutein and zeaxanthin isomers (RR- and RS). They offer protection to the eyes for enhanced vision and memory boost. 
Stress Reduction The formula helps to lower mental stress and could also motivate you to finish a set project. 

Pros And Cons


  • Science-based ingredients. 
  • Zero prescription. 
  • Money-back guarantee with free shipping. 
  • Caffeine-free, grain-free, and non-GMO.
  • Big savings on bundles.
  • Satisfaction guaranteed.


  • May not be safe for children. 
  • Could take some time before showing significant results. 

Noocube Pricing Plans

Here are the selling prices of Noocube packages. 

  • 1 bottle (60 Capsules) + Fast And Free Shipping = ($64.99)
  • 2 bottles (180 capsules) + 1 Free Bottle + Fast And Free Shipping = ($129.99)
  • 3 bottles (360 Capsules) + 3 Free Bottles + Fast And Free Shipping = ($194.99)

If you are unsatisfied with Noocube after 30 days, contact the customer care support team for a 100% money-back guarantee of your unopened package(s).

3. Nooceptin


Nooceptin is a brain-enhancing dietary supplement designed to enhance your problem-solving skills while protecting your brain cells. The formula is made with natural ingredients that are seamlessly blended in a strict standard for quality assurance and purity.

It is claimed to be manufactured in an FDA-inspected facility into capsules that are non-GMO. It has a refund policy and great positive customer reviews. 

Nooceptin Ingredients List

The following ingredients are used in Nooceptin’s production.

Panax Ginseng Extract 200 MgKnown for anxiety and stress control. It is an anxiolytic, meaning, it helps in anxiety suppression. Studies have found that ginseng can protect the brain from damage engendered by free radicals.
Lion’s Mane ExtractFor long-term cognitive performance. It contains two nootropic compounds known as erinacines and hericenones. According to studies, erinacines and hericenones can trigger Nerve growth factor release in the brain. NGF helps in neurons’ survival and growth. 
Ginkgo Biloba Extract 200 MgRich in glycosides and terpenes, GBE increases blood flow to the brain leading to cerebral vessel dilation. The result is improved circulation in the brain. Immediate cognitive performance is noticed after consuming this ingredient. 
L-TheanineStudies reveal that taking large quantities of this amino acid can have significant effects on cognitive performance. Also found to increase serotonin, dopamine, and GABA in the brain. These neurotransmitters aid relaxation and positive mood. 
Bacopa Monnieri Extract 150 MgIt promotes dendrite outgrowth resulting in brain functions. One study found that Bacopa Monnieri increased BDNF levels in the brain. 

Benefits Offered By Nooceptin

Cognitive FunctionsThe ingredients work in synergy to trigger thought sharpness and smart work performance. 
Anxiety ControlNooceptin is designed to help you manage stress calmly and productively.  
RecollectionThe ingredients are replete with vitamins and other nutrients for memory recollection and sharp retention.
Brain Regeneration This dietary nootropic helps in brain regeneration and neuron growth. 
Energy SupplyThe formula helps to keep you energetic without inducing fatigue and lethargy. 
Mental AlertnessThe manufacturing ingredients supply the brain with nutrients that trigger mental clarity and sharp focus.

Pros And Cons


  • Made in an FDA-inspected facility.
  • Anybody can use it.
  • Fast and discreet shipping is available. 
  • Affordable. 
  • Clinically-proven ingredients.


  • Available only on the official website. 
  • It could take about 16 weeks to see optimal results.

Nooceptin Pricing Plans

Here are the prices offered on the official website. 

  • 1 bottle (1-Month Supply) + Fast And Tracked Shipping = ($69)
  • 2 bottles (2-Month Supply) + Fast And Tracked Shipping + $16 Savings = ($138.00) 
  • 3 bottles (3-Month Supply) + Fast And Tracked Shipping + $18 Savings = ($207.00)

Use after 30 days and if you are not pleased with the result, call in for a 100% money-back guarantee. 

4. Vyvamind


Vyvamind is claimed to be a natural fast-acting neurostimulator for adults who struggle with focus and energy for work performance. The dietary formula is said to be ideal for students, programmers, traders, and anybody else who needs to be focused while learning.

It’s made with natural ingredients that are blended using modern, FDA-approved, and GMP-certified facilities under strict conditions for purity. The capsules are easy to swallow and show no side effects. 

Vyvamind Ingredients List

Vyvamind is composed of the following natural ingredients: 

CiticolineMade of Choline and Cytidine, Citocoline energizes the brain for focus and productivity. Supports neurotransmitters in the brain and offers them protection by raising antioxidant properties. 
L-Tyrosine 300 MgThis amino acid is naturally produced in the body from phenylalanine. It makes you perform better under pressure. Also known to promote memory, mood, and mental processing.  
L-Theanine 150 MgAn amino acid found in tea leaves and some mushrooms. Prevents jitters from stimulants through a reduction in excitable neurotransmitter effects. It fights brain neuron damage in old age. 
Caffeine Anhydrous 75 MgNatural stimulants found in coffee, cocoa, and tea, caffeine binds with adenosine receptors in the brain, blocking adenosine from accessing your brain. Hence leading to energy, focus, and cognition. 

Benefits Offered By Vyvamind

Stress And Anxiety Reduction The ingredients used help reduce stress and anxiety thereby improving good living conditions. 
Focus And ClarityVyvamind supplies energy, eliminates mental fatigue and triggers brain power. 
Increased Motivation And DriveHelps in long thought formation, problem solving, and a good night’s sleep. 
Brain Power Boost Helps provide instant long-lasting effects when needed. 
Advanced Burnout Protection For mental fatigue and depression elimination. 

Pros And Cons


  • Has no side effects.
  • Safe for consumption.
  • No prescription is required. 
  • Capsules are easy to swallow.
  • Secure and free order shipping 
  • Money-back guarantee. 


  • Unsuitable for children under 18 and pregnant women. 
  • Not recommended for unhealthy people. 

Vyvamind Pricing Plans

Vyvamind is offered at the following prices. 

  • 1 bottle (1-Month Supply) + $5.01 Savings + Fast And Tracked Shipping = ($74.99)
  • 2 bottles (2-Month Supply) + $20.02 Savings + Fast And Tracked Shipping = ($139.98)
  • 3 bottles (3-Month Supply) + $33.0 Savings + Fast And Tracked Shipping = ($207.00)

Use the product for 30 days. If it doesn’t seem to produce your desired result, contact for a full refund backed by a 100% money-back guarantee. 

5. Neurodrine


Neurodine is claimed to be a 2023 breakthrough formula responsible for healthy brain and memory function. It is composed of plants and herbs that are uniformly blended in a sterile condition and FDA-approved and GMP-certified facilities.

Designed into pills that are easy to swallow, the formula is said to be efficacious according to customer’s opinions. It is supported by a 364-day full refund policy. 

Neurodrine Ingredients List

Here are some of the ingredients that make up Neurodrine. 

Bacopa MonnieriBy boosting brain-derived neurotrophic factors, Bacopa supports memory.  To learn more about Bacopa, read the previous reviews on this page. 
Huperzine AThis plant-based ingredient acts like a bulletproof jacket for your brain. Its main function is protection. 
St. John’s WortFor protection against oxidative and daily stress.
Ginkgo BilobaFor working support and long-term memory protection thereby enhancing neural pathways. 
L-glutamineFor increase in mental alertness, mood, focus, and concentration.
VinpocetineFor learning and memory facilitation. For prevention of cognitive dysfunctions relative to dementia. 

Benefits Offered By Neurodrine

Mental Clarity Neurodrine helps in sharp memory and retention capacity. Also found to support focus. 
Healthy Brain SupportAll the natural ingredients combined help to foster the brain’s health for overall cognitive functions. 
Oxidative And Stress Reduction Ingredients like St. John’s Wort help in managing stress by reducing its effects on your body. 
Memory BoostFor improved recollection and learning processes.  

Pros And Cons


  • No reported side effects.
  • Money-back guarantee.
  • Made in FDA-approved facilities. 
  • It’s safe for consumption.
  • Affordable pricing with discounts. 


  • Not recommended to be taken with other supplements
  • You may not be able to take it with a medical condition. 

Neurodrine Pricing Plans

Here are the discounted prices for Neurodrine according to the official website. 

  • 1 bottle (1-Month Supply) = ($69)
  • 3 bottles (3-Month Supply) + 2 Free Bonuses + Free US Shipping = $177 ($59/Bottle)
  • 6 bottles (6-Month Supply) + 3 Free Bonuses + Free US Shipping = $294 ($49/Bottle)

If after using this nootropic for 364 days you are not pleased with how you feel, you can call in for a 100% money-back guarantee. 

How We Ranked The Top 5 Best Nootropic Supplements – Ranking Factors

The following factors were considered in ranking the best nootropic supplement in 2023

  • Ingredients Used

The naturalness of the ingredients used in their formulation was considered before rating them as the best. During the review, we found out that all the ingredients used for each of the five nootropics were natural and plant-based with no chemical mixture. 

  • Manufacturing Environments 

All five of them were produced in strict conditions with FDA-approved and GMP-certified facilities. 

  • Clinical Research

Consideration was given to the research behind the supplements as a rating factor. They were found to have undergone clinical trials conducted by renowned universities such as Leed.

  • Consumption Safety And Result Duration 

How safe are they for consumption and how long are obvious results seen? These were also considered. All the brain enhancers were found to produce results about the first month of intake and no side effects were found.


Detailed reviews of the top 5 best nootropic supplements in 2023 have been conducted. The analysis revealed that the supplements are made with natural ingredients from facilities approved and certified by authorized bodies.

Their advantages outnumber the disadvantages. A lot of positive reviews abound online regarding the supplements and each of them is supported with a money-back guarantee. They show no side effects being soy-free, grain-free, and stimulant-free.

Made into non-GMO capsules, these five nootropic supplements were found easy to ingest with water. Considering these findings, you can confidently give these top 5 nootropics supplements a try, they are safe to consume.


1. How were the top 5 best nootropic supplements in 2023 rated?

Certain factors such as manufacturing environment, consumption safety, and ingredients used were considered. 

2. In what form do they come?

They come in the form of capsules to be taken with water daily. 

3. What if I don’t like my result?

If you don’t like your result after the stated days, contact the support team for a money-back guarantee. 

4. Are the ingredients safe?

Yes, the ingredients are safe, natural, and free of chemicals. 

5. Who can take these five best pills?

Anybody above 18 years who wants to have a long memory, focus, and attention span.   

Dr. Jun Ren is a dedicated and experienced registered dietitian and nutritionist who is committed to helping people achieve their health goals through personalized nutrition plans. With a passion for promoting healthy eating habits and preventing chronic diseases, Dr. Ren has been able to assist numerous clients in improving their overall quality of life.

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