What Is Semaglutide For Weight Loss? Benefits Explained!


The medicinal drug was initially only recommended to treat diabetes.

Its potential in treating chronic weight management was discovered after the health agency approved the formula.

Following the outbreak of the research conducted, the general public came to know that obesity is one such condition to be considered like another chronic metabolic disease and that completing depending on changing the lifestyle wouldn’t suffice to treat it.

What Is Semaglutide? 

Semaglutide is an antidiabetic medication that is sold under the brand name Rybelsus, Wegowy, and Ozsemoic.

However, Semaglutide under the brand name Wegovy is only approved to take for weight management.

After the revolutionary outbreak of  Semaglutide as a medication for weight loss management, it is also being used to treat it. 

In June 2018, a group of scientists took Semaglutide as their subject of study clueless of its true potential.


Later, in 2012, a team of researchers at Novo Nordisk, a pharmaceutical company, came up with the original formula of Semaglutide, which they stated could be an alternative to liraglutide. 

The drug belongs to the class of Glucagon-like peptide-1 agonists, which are generally used to minister both type 2 diabetes and obesity.

Lately, it was also found that Semaglutide imitates the effects of GLP-1 as it helps in enhancing the capabilities of incretin function.

On top of this, Semaglutide also takes the initiative in suppressing hepatic gluconeogenesis as well as releasing glucagon, the two actions that unanimously work to reduce the amount of postprandial glucose in the human body. 

Clinical Trials Conducted On Semaglutide And Its Efficacy 

Clinical trials, which were divided into two stages, were conducted on Semaglutide, to find the efficacy of the medicinal drug.

At first, a group of individuals was chosen as participants, and they were injected weekly.

Half of the participants were entitled to get Semaglutide, whereas the other half received dummy medicine.

Who was to get the original blend of Semaglutide and who was to get the dummy medicine was decided by chance.

In addition to injecting this fluid once a week for the next 1.5 years, the participants were also supposed to have calls with doctors. 

After the main phase, the participants entered the extension phase which lasted for the next 3 years.

During this phase, they were only observed and not injected.

However, the results seemed to be favorable as adults taking the medicinal dose lost nearly 15% of their body weight, which was 12% more than those who took the dummy.

Therefore, it was concluded that Semaglutide had significant effects on weight loss as well as on weight management. 

Benefits And Considerations 

There are several dietary supplements and anti-obesity medications, available on the current market, that help to achieve weight loss, like Liv Pure and BioFit.

But, Semaglutide injection outshines them all with its effectiveness.

In simple words, Semaglutide allows instant calorie burn, thereby promoting weight loss.

Producing more insulation and reducing blood sugar levels are the other major benefits of Semaglutide. 

However, additional studies have shown that the majority of individuals who experienced the factorable results regained their initial weight when they stopped taking the drug.

In the wake of the findings, Dr. Vijaya Surampudi who is an Assistant Professor of Medicine at COMET, stated that the fundamentals of weight loss are confined to regular exercise and diet.

According to him, anti-obesity medications like Semaglutide injections are only “a tool in the toolbox.”

Often, the effectiveness of a supplement may depend on a person’s medical history.

That being said, there have been many cases where supplements that work well for a specific group of people end up inducing certain side effects in others.

So, minor side effects can also be expected from Semaglutide, regardless of its quality measures. 

What Are The Side Effects Of Semaglutide Injections? 

If the complications associated with obesity are something to go by, then the potential side effects of Semaglutide injection will only seem to be mild.

Usually, being overweight causes major threats such as coronary heart disease, stroke, high blood pressure, gallbladder disease, dyslipidemia, and, in some rare cases, death.

When compared to that, the side effects are only negligible. It only ranges from dizziness to stomach issues like vomiting, diarrhea, and constipation. 

Among these, gastrointestinal issues are frequently reported by people who are in the early stage of Semaglutide usage.

Nevertheless, experts recommend starting with a lower dose and then slowly adding on to it. 


Often, people misjudge Semaglutide injections as a dietary supplement, whereas the two are entirely different from one another.

Semaglutide is scientifically proven to work as an anti-obesity medication, and it is also approved by FDA.

Due to its effectiveness as a weight loss promoter, the demand for the drug has increased to the extent that there is a significant shortage of Semaglutide for diabetic patients. 

However, before buying Semaglutide, considering a medical expert should be the first step taken so that you may know whether or not Semaglutide is suitable for you. 

Dr. Jun Ren is a dedicated and experienced registered dietitian and nutritionist who is committed to helping people achieve their health goals through personalized nutrition plans. With a passion for promoting healthy eating habits and preventing chronic diseases, Dr. Ren has been able to assist numerous clients in improving their overall quality of life.

Leave a Comment