DOI:
Abstract
Background: Acute myocardial infarction (AMI) is one of the leading causes of morbidity and mortality across the world. Very few studies were done to see the association of renal function tests and serum electrolytes with acute myocardial infarction. Objectives: To study the renal function tests like blood urea and serum creatinine with serum electrolytes like serum sodium, potassium and chloride in patients with acute myocardial infarction. Material and Methods: This case control study was carried on 50 AMI patients and 50 healthy controls. 5 ml of blood was drawn from each patient within 6 hrs. of AMI, to estimate blood urea, serum creatinine, serum sodium, serum potassium, serum chloride and cardiac marker CK-MB. The same biochemicals were also determined in 50 age and gender matched controls for comparison. Results: We found significantly increased levels of blood urea and serum creatinine in AMI patients as compared to controls. We also found statistically significant decreased levels of serum sodium, serum potassium and non-significant difference in the levels of serum chloride in AMI cases as compared to controls. Conclusion: We found altered changes in the blood urea and serum creatinine in AMI with hyponatremia and hypokalemia which may act as indicator of injury to myocardium. Further studies are needed to correlate all these parameters with the prognosis of AMI.
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