Preparation and evaluation of iopamidol Parenteral formulation

  • Kamlesh Machewar Taywade College of Pharmacy, Mahadula, Koradi Colony Tah.: Kamptee, Dist.: Nagpur - 441111 (Maharashtra)
  • Vijendra Kharabe Bhopal Institute of Technology & Science, Bhopal, Madhya Pradesh 462045
Keywords: iopamidol, Parenteral formulation, contrast media

Abstract

Parenteral administration offers many advantages over therapy, given by non parenteral routes. Most notably, therapeutics can reliably predict with considerably accuracy, the Pharmacokinetic and Pharmacology of the agents. Despite of these advantages, parenteral administration is not without certain, measurable risks and limitation that the professional must intelligently weigh in terms of risks benefits, and costs. Iopamidol is radio opaque Nonionic contrast media used parenterally for diagnostic purpose. Solubility of iopamidol is very limited in water. Various Marketed formulations suffer the problem of crystallization of Iopamidol; such crystallization is very crucial as it will vary the dose and also effective drug in the solubilized form is minimized.

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Published
2014-06-30
How to Cite
1.
Machewar K, Kharabe V. Preparation and evaluation of iopamidol Parenteral formulation. IJAP [Internet]. 30Jun.2014 [cited 24Oct.2018];3(3):32-5. Available from: https://ssjournals.com/index.php/ijap/article/view/4430
Section
Research Articles