Reference Interval for Renal Profile parameters in North Indian Population from Rajasthan
Objective: Reference intervals are an essential part of laboratory medicine. Current study was planned to evaluate renal parameters in the healthy defined group of individuals which would serve as reference values of renal parameters for the North Indian population from Rajasthan.
Design & Methods: Present study was conducted on 2021 apparently healthy individuals of North Indian origin ranging in age from 15-60 years, were selected randomly using defined criteria. Fasting samples were analyzed for Urea, Creatinine, Uric Acid, Sodium, Potassium and Chloride. Data were analyzed for middle 95 percentile (2.5th-97.5th percentile), median and 95% confidence interval using SPSS software package version 10.0.
Result: RI for Urea, Creatinine and uric acid were lower in female (16-42mg/dl, 0.6-1.2mg/dl, 2.4-6.8mg/dl) as compared to male (17.00-44.35mg/dl, 0.7-1.5mg/dl, 2.8-7.2mg/dl). There was a progressive increase in urea, uric acid and Creatinine with increase in age. Though no appreciable differences could be observed in respect to most of renal parameters in rural versus urban, a wider range for uric acid was observed in urban population (2.50-7.20mg/dl). Except for Na+, K+ and Cl-, rest of parameters i.e. urea, creatinine, uric acid were higher range in obese as compared to non obese (17-45 Vs 17-44, 0.66-1.5 Vs 0.60-1.40, 2.5-7.4 Vs 2.5-7.0). Uric acid level was also found to be higher in non vegetarian population (2.6-7.5mg/dl).
Conclusion: Findings of this study provide sex, age, BMI, habitat and diet specific renal function reference values to be used for North Indian population.
Copyright (c) 2015 International Journal of Advances in Scientific Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).
- The author must Submit Copyright form After acceptance of Article.