An updated review on transdermal drug delivery systems

  • Audumbar Digambar Mali Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola- 413307, Solapur, Maharashtra, India.
  • Ritesh Bathe Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra
  • Manojkumar Patil Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra
Keywords: Transdermal drug delivery systems (TDDS), Diffusion, First-generation TDS, Second-generation TDS, Polymer Matrix, Permeation enhancers, Iontophoresis, Microneedles

Abstract

Transdermal drug delivery systems (TDDS), also known as “patches,” are dosage forms designed to deliver a therapeutically effective amount of drug across a patient’s skin. In order to deliver therapeutic agents through the human skin for systemic effects, the comprehensive morphological, biophysical and physicochemical properties of the skin are to be considered. Transdermal delivery provides a leading edge over injectables and oral routes by increasing patient compliance and avoiding first pass metabolism respectively. Transdermal delivery not only provides controlled, constant administration of the drug, but also allows continuous input of drugs with short biological half-lives and eliminates pulsed entry into systemic circulation, which often causes undesirable side effects. The TDDS review articles provide valuable information regarding the transdermal drug delivery systems and its evaluation process details as a ready reference for the research scientist who is involved in TDDS. With the advancement in technology Pharma industries have trendified all its resources. Earlier we use convectional dosage form but now we use novel drug delivery system. One of greatest innovation of novel drug delivery is transdermal patch. The advantage of transdermal drug delivery system is that it is painless technique of administration of drugs.

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Author Biography

Audumbar Digambar Mali, Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola- 413307, Solapur, Maharashtra, India.
Pharmaceutics Department and First rank in solapur university,solapur.
Published
2015-07-30
How to Cite
1.
Mali A, Bathe R, Patil M. An updated review on transdermal drug delivery systems. IJASR [Internet]. 30Jul.2015 [cited 9Dec.2018];1(6):244-5. Available from: https://ssjournals.com/index.php/ijasr/article/view/2243
Section
Review Articles

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