Evaluation of thyroid profile status in women with abnormal uterine bleeding in north Indian population

  • Musarrat Parveen Department of Biochemistry, Patna Medical College and Hospital, Patna
  • Sweta Kumari Department of Biochemistry, Vardhman Institute of Medical Sciences, Pavapuri, Nalanda
  • S. S. Haque Department of Biochemistry, Indira Gandhi Institute of Medical Sciences, Patna-14
  • Ravi Kumar Department of Biochemistry, Indira Gandhi Institute of Medical Sciences, Patna-14
Keywords: Abnormal uterine bleeding, Menorrhagia, Oligomenorrhoea, Hypothyroidism, Hyperthyroidism

Abstract

Background: Abnormal Uterine Bleeding is a common complication occurs in 9 14% of women from Menarche to Menopause. Women are more prone to thyroid disorder and cause abnormal sexual development, menstrual irregularity, infertility and premature menopauseMy objective of studyis to evaluate the thyroid function tests in women with abnormal uterine bleeding in north Indian population.

Methods: After selecting the women, informed consent was obtained. The case history and clinical examination of them were done, requested to do thyroid functioning test in fasting status in early morning and the results were evaluated. Thyroid function tests were estimated by Chemiluminescence Immuno Assay (C.L.I.A) method using reagent Monobind I N C with the help of fully automatic Elecsys 2010 machine made by ROCHE.

Results: There were 150 women who were included in the study. Out of all the types of commonest symptoms were menorrhagia. around 47%. Patients with oligomennorrhoea had hyperthyroidism in 16.7% of patients, hypothyroidism in 8.3% of patients and subclinical hypothyroidism in 8.3%. In polymenorrhoea patients 42.9% of cases had subclinical hypothyroidism.

Conclusions: As there is high incidence of thyroid diseases in a north Indian population, women with abnormal uterine bleeding. This would also avoid unnecessary hormonal treatment and surgical intervention in these patients.

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Published
2017-08-01
Section
Original Research Articles