Comparative study between Nalbuphine and Dexmedetomidine as an adjuvant to Ropivacaine for Caudal Block in children undergoing infra umbilical surgeries
Background and Aims: The quality of caudal blocks can be improved by adding adjuvants to the local anaesthetic. Adjuvants prolong analgesia and decrease the adverse effects encountered with single high dose local anaesthetic. The objective of this study was to compare caudal nalbuphine and dexmedetomidine combined with ropivacaine to provide postoperative analgesia in children undergoing infra-umbilical surgeries.
Material and Methods: This was a randomised, prospective double blinded study. A total of 60 children aged 1-12 years were randomly allocated into 2 groups: Group A received caudal block with 0.2% ropivacaine 1ml/kg with 0.2mg/kg nalbuphine and Group B received caudal block with 0.2% ropivacaine 1ml/kg with dexmedetomidine 2 µg/kg. Duration of analgesia, haemodynamic changes and adverse effects were compared. Percentage analysis and independent sample t-test were used. Chi square analysis was used for categorical variables.
Results: Group A recorded duration of analgesia of 5.8± 0.88 hours, compared to 9.1 ±0.89 hours in group B and this was statistically significant. All 30 patients in group B had lower pain scores at 4th, 5th and 9th hours.
Conclusion: caudal ropivacaine 0.2% (1ml/kg) with dexmedetomidine 2 µg/kg resulted in prolongation of duration of analgesia and better quality of analgesia compared with ropivacaine 0.2% (1ml/kg) with nalbuphine 0.2mg/kg without any significant difference in the haemodynamic parameters.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).
- Author must Submit Copyright form After accepetance of Article.