Circulating magnesium & Acute phage inflammatory reactant in North Indian adult population

  • Geeta Shamnani Assistant Professor, Department Of Physiology, RKDF MCH RC, Bhopal
  • Vani Gupta Professor, Department of Physiology, King George’s Medical University, Lucknow, UP.
  • Charushilla Atul Rukadikar Assistant Professor, Department of Physiology, CMC & Hospital, Bhopal, MP
  • Shraddha Singh Professor, Department of Physiology, King George’s Medical University, Lucknow, UP,
  • Sunita Tiwari Professor, Department of Physiology, King George’s Medical University, Lucknow, UP,
  • Shekhawat Singh Bhartiy SMO, World Health Organization
Keywords: Circulating magnesium, acute phase inflammatory reactants, cross-sectional study, hypomagnesemia, C-reactive protein, North Indian adult population


Background: The increase of several serum proteins named acute phase reactants is a feature of the tissue response to inflammation. C-reactive protein (CRP) is one of the most sensitive acute-phase reactants in humans. Magnesium is found to be associated with these inflammatory reactants in previous studies.

Objectives: The aim of this study was to investigate the relationship between serum magnesium levels and C- reactive protein in apparently healthy adults.

Methods and material: This is a population based cross-sectional study. Total 130 adults of age between 25-65 years, were recruited with prior ethical approval and with written informed consent.  

Result: Mean value of serum magnesium was found to be 2.01mg/dl (±0.29) with range between 1.4mg/dl to 2.9mg/dl. Not a single case of severe hypomagnesemia (< 1.2 mg/dl) was found. Serum magnesium was found to have no significant correlation with C-reactive protein (r = -0.12, p=0.23).

Conclusion: Authors report no significant co-relation between serum magnesium and CRP. Further larger studies are required to be done.


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How to Cite
Shamnani, G., Gupta, V., Rukadikar, C., Singh, S., Tiwari, S., & Singh Bhartiy, S. (2018). Circulating magnesium & Acute phage inflammatory reactant in North Indian adult population. International Journal of Biomedical and Advance Research, 9(4), 171-174.
Original Research Articles