Comprehensive Analysis of Lipid Profile in Diabetic patients in Jamnagar, Gujarat
Objectives: Nearly 415 million world population is affected by diabetes mellitus (DM). Changes in lipid profile has been investigated to be associated with DM. Present study thus has conducted comprehensive analysis of lipid profile in DM.
Methods: 50 cases each of Type 1 DM, Type 2 DM & control were included in present study which was conducted at Guru Gobindsinh Hospital, Jamnagar, Gujarat by Physiology department, M. P. Shah medical college. Apart from FBS and urine sugar, lipid profile (i.e. S. Cholesterol, S. Triglyceride, S. HDL, S. VLDL, S. LDL) was done using enzymatic colorimetric tests. Prior consent was taken from patients.
Results: 72% cases in S. cholesterol, 74% cases in S. triglyceride, 72% cases in S. VLDL, 78% cases in S. LDL were found to be higher in Type 2 DM but with 30% of cases having low S. HDL level, it was inconclusive for association with Type 2 DM. However, majority of cases of Type 1 DM had all lipid profile levels within normal range.
Conclusion: Results were comparable for both Type 1 & 2 DM with Mrunalini et al and Carolyn et al studies except for mean S. VLDL which was higher in present study compare to Carolyn et al study. To conclude Lipid profile was on higher side for Type 2 DM (except S. HDL which was inconclusive) but normal for Type 1 DM in majority of cases. In females’ lipid profile was on higher side for all cases included in comparison to males.
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