Effect of calibration frequency on coefficient of variation observed with internal quality control samples for Glucose, Total Protein, Iron and Unsaturated Iron Binding Capacity

  • Shilpi Shloka Biochemistry Department, Government Medical College (GMC), Opp Income Tax Department Office, Majura Gate, Surat, Gujarat 395001
  • Manmeet Kochar
  • Niral Savaliya
  • Chapal Debnath
  • Shaileshkumar Manubhai Patel

Abstract

Objectives: The study aims at comparing precision of Glucose, Total Protein, Iron and Unsaturated Iron Binding Capacity assays between lot calibration and daily calibration. Methods: For Glucose, Total Protein, Iron and Unsaturated Iron Binding Capacity calibration factors were derived during lot change as well as daily. Both types of calibration factors were used to derive results of internal quality control samples daily for 20 days. Coefficient of variation for IQC results for both lot-calibration and daily-calibration were measured. Results and conclusions: CV% observed for daily calibration was higher than lot-calibration for total protein, glucose and Iron. While CV% observed for daily calibration were lower than lot-calibration for UIBC. It is concluded that optimum frequency of calibration differs for each examination and depends on robustness of testing process for each analytes.

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Published
2018-12-30
How to Cite
Shloka, S., Kochar, M., Savaliya, N., Debnath, C., & Patel, S. (2018). Effect of calibration frequency on coefficient of variation observed with internal quality control samples for Glucose, Total Protein, Iron and Unsaturated Iron Binding Capacity. International Journal of Biomedical and Advance Research, 9(12), 412-416. https://doi.org/10.7439/ijbar.v9i12.4955
Section
Original Research Articles

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