Phytochemical analysis, antimicrobial activity and identification of phytoconstituents in Gleichenia pectinata (Willd.) C. Presl.

  • Abiola Femi-Adepoju Kwara State University
  • Paul O. Fatoba Department of Plant Biology, University of Ilorin, Ilorin
  • Adeyinka Adepoju, Dr. wesley University of technology, Ondo
  • Abimbola P. Oluyori Department of Physical Sciences, Landmark University, Omu-Aran, Kwara State
Keywords: ferns, Gleichenia pectinata, Chromatography, Fractionation, Antimicrobial


Probing into the bioactive chemical composition of ferns may lead to a validated incorporation into drug manufacture, though they belong to the unpopular group of plants. This present study aimed at investigating the phytoconstituents and antimicrobial potency of the raw methanolic extract and the active chromatographic fractions of Gleichenia pectinata. The phytochemical investigation was done via chemical and instrumental (GC-MS) method. The raw methanolic extract of G. pectinata contains important phytochemicals such as phenolics, terpenoids, anthraquinone, tannin, alkaloid, saponin, reducing sugar, protein and flavonoids. The minimum inhibitory concentration of the raw methanolic extract against the clinical microbial strains used was 25mg/ml against (Pseudomonas aeruginosa and Klebsiella pneumoniae). At this concentration, some G.pectinata chromatographic fractions exhibited significant antibacterial and antifungal activities. Pseudomonas aeruginosa and Klebsiella pneumoniae were the most susceptible of the test microorganisms while Candida albicans was the least susceptible.


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How to Cite
Femi-Adepoju, A., Fatoba, P., Adepoju, A., & Oluyori, A. (2018). Phytochemical analysis, antimicrobial activity and identification of phytoconstituents in Gleichenia pectinata (Willd.) C. Presl. International Journal of Biomedical and Advance Research, 9(12), 400-406.
Original Research Articles