Clinical Outcomes of Successful Sirolimus-Eluting Stent Implantation in Patients with Chronic Total Occlusion in the Real Clinical Practice

Outcomes of SES in CTO

  • Vijaya Pamidimukkala Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Murali Babu Rao Rachaputi Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Michael Noronha Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Srinivasa Rao Chinta Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Veera Prasada Rao Ravela Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Maruthi Prasad Immadisetty Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Lakshmi Sudha Prasanna Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Anurag Polavarapu Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Sravanthi Byrapaneni Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Naren Polavarapu Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Sirichandana Gangasani Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Ramesh Nelluri Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Nutakki Srinivas Rao Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Soma Srinivas Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Jangamasetty Mohan Murali Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Meghana Chilukuri Mahatma Gandhi Memorial Hospital, Warangal, Telangana-506007
  • Gadicharla Rajasekhar Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Kurgodu Math Manjunath drpvraghav@gmail.com
  • Nagam Raghu Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Elamandala Sree Charan Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Ramanaboina Venkata Subbaiah Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Tino Baby Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Pamidi Rajendra Kumar Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Katkojvala Ranjith Kumar Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Marella Rajya Lakshmi Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh 522001
  • Raghava Sarma Polavarapu Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh
  • Asif Raheem Yashfeen Cardiac Hospital, Navsari, Gujarat 396445
  • Kamlesh Thakkar Lions Sterling Super Specialty Hospital, Mehsana, Gujarat 384001
  • Jayesh Prajapati Apollo Hospitals, Ahmedabad, Gujarat 382428
Keywords: Coronary occlusion, drug-eluting stent, percutaneous coronary intervention, sirolimus, target lesion failure

Abstract

Objectives: We aimed to evaluate the clinical outcomes in patients with chronic total occlusion treated with Indolimus, biodegradable polymer coated sirolimus-eluting stent, in real clinical practice.

Methods: We evaluated clinical outcomes in 170 patients, who underwent successful recanalization of chronic total occlusion with Indolimus between April-2012 and June-2014. During 9-month, primary endpoint was target lesion failure (TLF), a miscellany of cardiac death, myocardial infarction (MI), target lesion revascularization(TLR) and target vessel revascularisation. We considered stent thrombosis as a clinical outcome parameter.

Results: The mean age was 50.7 years and 142(83.5%) patients were predominantly male. The average stent length and diameter were 30.8 ±8.4 mm and 3.1 ±0.4 mm, respectively. The cumulative TLF at 9-month was 2.9% which included one, one and three cases of cardiac death, TLR and MI, respectively.

Conclusion: In real clinical practice, treatment of chronic total occlusionwith Indolimus sirolimus-eluting stent showed favourable clinical outcomes with high success rates.

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Published
2019-02-13
How to Cite
Pamidimukkala, V., Rao Rachaputi, M. B., Noronha, M., Rao Chinta, S., Rao Ravela, V. P., Immadisetty, M., Prasanna, L., Polavarapu, A., Byrapaneni, S., Polavarapu, N., Gangasani, S., Nelluri, R., Rao, N., Srinivas, S., Murali, J., Chilukuri, M., Rajasekhar, G., Manjunath, K., Raghu, N., Charan, E., Subbaiah, R., Baby, T., Kumar, P., Kumar, K., Lakshmi, M., Polavarapu, R., Raheem, A., Thakkar, K., & Prajapati, J. (2019). Clinical Outcomes of Successful Sirolimus-Eluting Stent Implantation in Patients with Chronic Total Occlusion in the Real Clinical Practice. International Journal of Biomedical and Advance Research, 10(2), e5051. https://doi.org/10.7439/ijbar.v10i2.5051
Section
Original Research Articles