Evaluation of the Relevence of Touch Imprint Cytology in the diagnosis of Neoplastic lesions of Breast

  • Saritha Karre Kamineni Institute of Medical Sciences, Narketpally, Nalgonda, Telangana, India
  • Satyanarayana Veeragandham H.O.D, Department of Pathology, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda
  • Raghu Kalahasti Associate professor, Department of Pathology, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda.
  • Salma Mahjabeen Associate professor, Department of Pathology, Dr. VRK Women’s Medical College Aziznagar, R.R. district, Telangana.
  • Ashok Kumar Deshpande Associate Professor, Department of Pathology, Kamineni Institute of Medical Sciences, Narketpally,Nalgonda.
  • Sikinder Hayath Mohammed H.O.D, Department of Blood Transfusion, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda.
Keywords: imprint cytology, FNAC, histopathology, benign, malignant

Abstract

Imprint cytology (IC) is an easy, quick and inexpensive diagnostic method. IC is an accurate and simple intra operative method for diagnosing breast lesions and also used for various lesions in the body. The present study aims at comparing the touch IC with histological diagnosis, evaluating the accuracy of IC in diagnosis of benign and malignant lesions of breast and to compare the validity of touch IC with Fine needle aspiration cytology (FNAC). This was a descriptive study done in collaboration with Department of General Surgery at Kamineni Institute of Medical Sciences (KIMS) hospital, Narketpally. Fifty cases of breast lesions were evaluated, comprising of benign & malignant lesions. Relevant clinical data were recorded in a proforma. Touch imprints were prepared from all the lesions and stained with rapid Haematoxylin & Eosin (H&E) and routine H&E stains. The imprints were subsequently compared with cytology and histopathology examinations. We observed better accuracy in IC (96%) than FNAC (89%) in correlation with histopathology, better sensitivity in IC (97.3%) than FNAC (93.3%) in correlated well with histopathology, better specificity in IC (92.3%) than FNAC (50%) in correlation with histopathology, Predictive value-97.29%, Negative predictive value-92.3%. All the imprints were well corroborated with FNAC & histopathological diagnosis. Thus, IC provides initial diagnosis to surgeons for immediate clinical and surgical intervention.

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Author Biography

Saritha Karre, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda, Telangana, India
Department of Pathology, Assistant Professor.
Published
2014-11-30
How to Cite
1.
Karre S, Veeragandham S, Kalahasti R, Mahjabeen S, Deshpande AK, Mohammed S. Evaluation of the Relevence of Touch Imprint Cytology in the diagnosis of Neoplastic lesions of Breast. IJBR [Internet]. 30Nov.2014 [cited 9Dec.2018];5(11):709-14. Available from: https://ssjournals.com/index.php/ijbr/article/view/1114
Section
Original Research Articles