Assessment of the efficacy of dexamethasone, lignocaine or placebo in the prevention of post intubation sore throat
Objective:To assess the incidence of sore throat and hoarseness caused by endotracheal intubation.To observe if lignocaine or dexamethasone throat spray would alter the incidence of sore throat
Materials and methods: Adult patients of either sex who underwent general anaesthesia with endotracheal intubation were included in this randomised double blind study. Three hundred patients who had general anaesthesia with endotracheal intubation were randomly allocated into three groups Group A, Group B and Group C following block randomisation. Nature of the study was explained to the patient and verbal consent obtained. Group A 2ml of dexamethasone (8mg) was sprayed Group B 2ml of 4% lignocaine was sprayed in this group.Group C 2ml of normal saline was used in this group.Postoperatively between 12-24 hours patients were invited to find out if any sore throat or hoarseness of voice was present. Verbal analogue scoring system was used.
Results:Postoperatively sore throat was present in 26% in group A, 33% in group B and 28% in group C. Hoarseness was present in 20% in group A, 23% in group B and 18% in group C. Sore throat and hoarseness were present in 37% in group A, 45% in group B and 39% in group C.
Conclusion: Neither dexamethasone nor lignocaine throat spray were useful in reducing postoperative sore throat and hoarseness.
Copyright (c) 2015 International Journal of Biomedical Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- An author must submit Copyright form After acceptance of the article.