Assessment of neurodevelopmental abnormalities in children with severe acute malnutrition between the age of 6 months to 30 months

  • Vaibhav Jain Surya Children Medicare Private limited, Mumbai
  • Swati Patel Bai Jerbai Wadia Hospital, Mumbai
  • Neetu S Agarwal Department of Pediatrics, G. R. Medical College and Kamla Raja hospital, Gwalior
  • Ajay Gaur Department of Pediatrics, G. R. Medical College, and kamla Raja hospital, Gwalior
Keywords: Severe Acute Malnutrition, Neurodevelopmental Assessment, DASII.

Abstract

Objectives: To assess the developmental abnormalities in Severe Acute Malnutrition using Developmental Assessment Scale for Indian Infants (DASII).

Design: Hospital based Prospective Analytical Study.

Setting: Department of Pediatrics, Kamla Raja Hospital, Gajra Raja Medical College, Gwalior.

Participants: Children with severe acute malnutrition as per criteria of WHO between the age of 6 months and 30 months admitted in the hospital between March 2015 to January 2017.

Method: Patients were first managed as per WHO guidelines of SAM. At the end of stabilization phase detailed neurological examination was done to look for neurological deficits by Development Assessment Scale for Indian Infants (DASII).

Results: A total of 70 cases were enrolled. Mean Development Quotient for cases was 79.7(23.5) against a population mean of 112.28(10.7) (p<0.001). Motor Development Quotient was found to be 79.56(23.03) (p<0.001) and Mental Development Quotient was 79.90(26.075) (p<0.001). MUAC was found to have positive correlation with Motor DQ (p value 0.006) with patients having MUAC<11.5cm having motor DQ [74.7(24.1)] as compared to those having MUAC >11.5cm [91.5(16.4)]. On analyzing patients having stunting, it was found that a significant proportion of them had low Motor DQ (chi2 4.1, p value 0.023), low Mental DQ (chi2 2.9, p value 0.038), and low Mean DQ (chi2 3.1, p value 0.036) when compared to patients not having stunting.

Conclusions: SAM patients have both low Mental DQ and Motor DQ. Low MUAC is associated with Low Motor DQ. Stunting is associated with low Motor and Mental DQ.

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Author Biographies

Vaibhav Jain, Surya Children Medicare Private limited, Mumbai
Senior Resident, department of pediatrics
Swati Patel, Bai Jerbai Wadia Hospital, Mumbai
Senior resident department of pediatrics
Neetu S Agarwal, Department of Pediatrics, G. R. Medical College and Kamla Raja hospital, Gwalior
Assistant professor
Ajay Gaur, Department of Pediatrics, G. R. Medical College, and kamla Raja hospital, Gwalior
Professor and head of department

References

National family health survey 3 (2006) data http://www.rchiips.org/nfhs/nfhs3.shtml. Accessed on 20/05/13

Amiel- Tison, C. A method for neurologic examination within the first year of life. Curr Probl Pediatr 1976; 7 (1): 1-50.

Phatak P, Misra N. Developmental Assessment Scales for Indian Infants (DASII) 1-30 months - Revision of Baroda Norma with indigenous material. Psychol Stud 1996; 41:55-56.

Chase HP, Martin HP. Undernutrition and child development. N Engl J Med. 1970; 282:933.

Caller JR, Ramsey F, Solimano G, Ku Charski LT, Harrison R. The influence of malnutrition on subsequent behavioural development. Pediatr Res. 1984; 18:826.

J M Celedon, I de Andraca. Psychomotor development during treatment of severe marasmic infants. Early Human Development, 1979, 313, 267-275

Bhoomika R Kar, Shobini L Rao, B A Chandramouli. Cognitive Impairment in children with chronic energy malnutrition. Behav Brain Funct. 2008; 4 : 31.

Published
2018-01-30
Section
Original Research Articles