Study of Electrolyte status in patients with Thyroid dysfunction attending a tertiary care hospital of North Bengal.
Context: Thyroid disorders have widespread systemic manifestations including their effects on body mineral homeostasis in many different ways. Thyroid hormones control urinary excretion of minerals like Magnesium, zinc, sodium, potassium etc and minerals like Zn helps in peripheral conversion of inactive T4 to its active T3 form. Electrolyte abnormality is a common finding in the patients with thyroid dysfunction which can effect the disease morbidity.
Aims & Objective: The present study was carried out to access the importance of Electrolyte status in the study subjects and to use the information for lowering the mortality and morbidity associated with the disease process.
Materials &Methods: The study population was divided into normal control group consisting of 40 healthy individuals and a test group consisting of 80 patients out of whom 40 were diagnosed to be having primary hypothyroidism and 40 to be having primary hyperthyroidism. Electrolyte status was assessed by serum calcium, serum phosphorus, serum magnesium, serum zinc, serum sodium and serum potassium
Results: There is a significant increase in levels of serum calcium and phosphorus in group-II (P<0.001) and significant decrease in their levels in group-I (P<0.001) compared to control. Serum Magnesium showed a significant decrease in test groups-II (P<0.001) and increase in test group-I (P<0.001) compared to controls. Serum sodium showed significant decrease in test group-I (P<0.001) and test group-II (P=0.007) but the study did not show any significant difference in level of serum zinc and potassium in test group-I and II when compared to controls.
Conclusion: Thyroid dysfunction results in an array of electrolyte abnormalities which increases the morbidity and mortality of the disease process. By proper maintenance of the electrolytes within normal limit, we can employ preventive strategies for better management of the patients and thereby improve their survival.
Copyright (c) 2018 International Journal of Biomedical Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- An author must submit Copyright form After acceptance of the article.