Clinical profile of HIV positive children
AbstractBackgrounds: HIV infection has become a pandemic affecting both industrialized and developing countries. The increase in pediatric HIV infection has had a substantial impact on childhood mortality both in industrialized countries and developing countries. The present research was carried out to study the clinical profile of pediatric patients admitted with HIV infection. Method: Total 55 cases of aged 1 month to 12 years, detected to be HIV-positive (on triple ELISA test) were enrolled in the study. HIV status of patients 18 months of age was confirmed by DNA-PCR testing. The demographic data of the patients, clinical features, investigations and outcome were recorded. Results: The majority [34 (61.81%)] of cases were in below 5 years of age with male predominant 38 (69.09%). The predominant route of transmission of HIV to the child was by perinatal transmission [51 (92.72%)] while four cases (7.27%) were infected via blood transfusion. Clinical features at presentation in 49 symptomatic cases included protein-energy malnutrition (89.79%), fever Ëƒ1 month (55.10%), weight loss Ëƒ1 month (51.02%), persistent generalized lymphadenopathy (22.44%) and skin manifestations (75.51%). The gastrointestinal (61.22%) and respiratory (57.14%) were the most commonly involved organ systems. Opportunistic infections were tuberculosis (21 cases), candidiasis (8 cases), Pneumocystis carinii pneumonia (3 cases), herpes zoster (4 cases) and giardiasis (1case). The mortality of the study was 9.09%. Conclusions: Perinatal transmission is the most common mode of acquiring HIV in the pediatric age group. Most patients have protein-energy malnutrition. Tuberculosis should be regarded as the indicator disease for HIV infection in children.
Download data is not yet available.
Abstract : 0 | PDF : 0
How to Cite
Bapat S. Clinical profile of HIV positive children. IJBR [Internet]. 1Apr.2018 [cited 19Apr.2019];9(3):117-20. Available from: https://ssjournals.com/index.php/ijbr/article/view/4723
Original Research Articles
Copyright (c) 2018 International Journal of Biomedical Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- An author must submit Copyright form After acceptance of the article.