A short review on sulphonamides with antimicrobial activity

  • Sonu . Department of Pharmaceutical Chemistry, S. D. College of Pharmacy and Vocational Studies, Bhopa Road Muzaffarnagar 251001
  • B Rabiya Parveen Department of Pharmaceutical Chemistry, S. D. College of Pharmacy and Vocational Studies, Bhopa Road Muzaffarnagar 251001
  • Sabiya Praveen Department of Pharmaceutical Chemistry, S. D. College of Pharmacy and Vocational Studies, Bhopa Road Muzaffarnagar 251001
  • Himanshu Pal Department of Pharmaceutical Chemistry, S. D. College of Pharmacy and Vocational Studies, Bhopa Road Muzaffarnagar 251001
Keywords: Antimicrobial activity Gram-negative bacteria, Gram-positive bacteria, Substituted Sulfonamides


Sulfonamides are one of the organosulphur compounds containing the -SO2NH2 and/or -SO2NH- group(s). The sulphonamides or sulfa drugs competitively inhibit folic acid synthesis in micro-organisms and subsequently inhibit multiplication of bacteria but do not actively kill them. They have been used against most gram-positive and many gram-negative bacteria, some fungi, and certain protozoa. Medically important sulphonamides


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