GC-MS analysis of anti-mark ointment formulation for skin burns

  • A. Shahanaz Laboratory for Venom Peptidomics and Molecular Simulation, Department of Biotechnology, Bannari Amman Institute of Technology, Erode, Tamil Nadu
  • G. Subiksha Laboratory for Venom Peptidomics and Molecular Simulation, Department of Biotechnology, Bannari Amman Institute of Technology, Erode, Tamil Nadu
  • M. Yuha Laboratory for Venom Peptidomics and Molecular Simulation, Department of Biotechnology, Bannari Amman Institute of Technology, Erode, Tamil Nadu
  • Gowri Shankar B A Laboratory for Venom Peptidomics and Molecular Simulation, Department of Biotechnology, Bannari Amman Institute of Technology, Erode, Tamil Nadu http://orcid.org/0000-0003-0612-3741
Keywords: GC-MS analysis, bioactive compounds, hair ash, anti-inflammatory.


Wounds generated from burns are fatal and cause marks that last for a long period of time. The formulation of anti marks cream especially for burns would provide hope for a better way of treating scars. The aim of this study is to prepare an ointment using hair ash and oil along with aloevera followed by the characterization of compounds by using Gas Chromatography and Mass Spectroscopy (GC-MS).The natural compounds used could possibly reduce any side effects on the skin. The GC-MS analysis of the ointment revealed the presence of 30 bioactive compounds. The predominant bioactive compounds were especially fatty acids such as hexadecanoic acid, tetradecanoic acid, dodecanoic acid and octadecanoic acid. The antibacterial, antioxidant, anti-inflammatory, antifungal properties of these bioactive compounds could be effectively used in the treatment of scars.


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Author Biography

Gowri Shankar B A, Laboratory for Venom Peptidomics and Molecular Simulation, Department of Biotechnology, Bannari Amman Institute of Technology, Erode, Tamil Nadu

Dr. B. A. Gowri Shankar, is an electrophysiologist, specialized in cardiac electrophysiology. His Master theis in Sydney, Australia, was on Structure comparison and Phylogenetic analysis of Cytochrome P450 family proteins, which aimed at understanding the evolution of CYP enzyme: How the structures have changed over time and between species and the significant changes in the drug binding site, which alters the function of the protein. His doctoral thesis at university of Vienna was on the modulation of voltage gated sodium channel by tyrosine kinases. He has worked with some of the best electrophysiology laboratories in Europe and a recipient of prestigious grant from European society of cardiology (ESC) to undergo postdoctoral training at K.U Leuven, Belgium. He was involved in identifying new Transient receptor potential (TRP) ion channels on the native isolated cardiac myocytes from pig and mouse using electrophysiology. He has varied field of interest (Bioinformatics, Biophysics and Molecular Biology) and .he wants to particularly involve in tricky cross-disciplinary areas like biophysics, molecular medicine, protein-structure function relationship and computational biology.


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