ANTITUMOR ACTIVITY OF CLEOME VISCOSA AGAINST EHRLICH ASCITES CARCINOMA (EAC) IN SWISS ALBINO MICE

  • Venu Gopal Yerragunta St. Peter’s Institute of Pharmaceutical Sciences, Warangal, A.P.
  • Ravindernath A College of Technology, Osmania University, Hyderabad
  • Kalpana G St. Peters Institute of Pharmaceutical Sciences, Warangal, A.P.
  • Prabhakar Reddy V St. Peters Institute of Pharmaceutical Sciences, Warangal, A.P
Keywords: Delta bilirubin, Hyperbilirubinemia, Jaundice, Sepsis

Abstract

Methanolic extract of Cleome viscosa (Cappareace)(MECV) wasevaluate for Antitumor activity using EAC bearing Swissa albino mice. The extract administered at a dose of 200 and 400 mg/kg body weight about for 14 days after 24 hr of inoculation.After 18 h of last dose animals were sacrifed then estimated for various tumor growth parameters like increase in life span,mean survival time, tumor volume, heamotological parameters. The tumor beraing mice has shown abnormal pattern of hemological parameters and decreased life span of tumor bearing mice.The extracts treatent broght back all the abnormal parameters of tumor bearing animals to normal. The results indicated that MECV exhibited antitumor activity against EAC bearing mice.

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Author Biography

Venu Gopal Yerragunta, St. Peter’s Institute of Pharmaceutical Sciences, Warangal, A.P.
Dept. of Pharmacology
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Published
2012-05-01
How to Cite
1.
Yerragunta V, A R, G K, Reddy V P. ANTITUMOR ACTIVITY OF CLEOME VISCOSA AGAINST EHRLICH ASCITES CARCINOMA (EAC) IN SWISS ALBINO MICE. IJPP [Internet]. 1May2012 [cited 19Apr.2019];2(2):pp.51-5. Available from: https://ssjournals.com/index.php/ijpp/article/view/1136
Section
Research Articles