Total polyphenol content and antioxidants capacity of three Africans antipyretic plants

  • Ayoman Thierry-Lenoir Djadji Laboratory Pharmacology, Clinical Pharmacy and Therapeutic: Laboratory of Pharmacology, UFR Pharmaceutical and Biological Sciences, Felix Houphouet-Boigny University
  • Donald Brou Koua Laboratory Pharmacology, Clinical Pharmacy and Therapeutic: Laboratory of Pharmacology, UFR Pharmaceutical and Biological Sciences, Felix Houphouet-Boigny University
  • Sandrine Any-Grah-Aka Sandrine Laboratory of Pharmacotechnic, Galenic Formulation and Pharmaceutical Legislation
  • Etienne Kouakou Effo Laboratory Pharmacology, Clinical Pharmacy and Therapeutic: Laboratory of Pharmacology, UFR Pharmaceutical and Biological Sciences, Felix Houphouet-Boigny University
  • Landry Sylvain Kouakou Laboratory Pharmacology, Clinical Pharmacy and Therapeutic: Laboratory of Pharmacology, UFR Pharmaceutical and Biological Sciences, Felix Houphouet-Boigny University
  • Genevieve Irie-N’Guessan Laboratory Pharmacology, Clinical Pharmacy and Therapeutic: Laboratory of Pharmacology, UFR Pharmaceutical and Biological Sciences, Felix Houphouet-Boigny University
  • Gisele N’Doua Kouakou-Siransy Laboratory Pharmacology, Clinical Pharmacy and Therapeutic: Laboratory of Pharmacology, UFR Pharmaceutical and Biological Sciences, Felix Houphouet-Boigny University

Abstract

Introduction: Ceiba P. Crossopteryx F. Pseudocedrela K . are used as a nutritional and medicinal (Antipyretic). The aim of this study was to perform the dosage of polyphenol content and their antioxidants capacity. Methods: Aqueous extracts of three plants leaves were used to determine polyphenol content using Folin-Ciocalteu and antioxidants activities by DPPH radical scavenging and FRAP Methods. Results: We found much more total phenol content in the leaves of Pseudocedrela K . respectively (352.57 mg/g). Antioxidants activities of pseudocedrela (279.9 mMol eq Trolox) by the Frap method was better than these others plants. (Trolox; R2= 0.9968). The IC50 = 12.1 µg/mL of leaves of pseudocedrela K. was inferior to two others plants ( Ceiba and crossopteryx ). That means that aqueous extract of Pseudocedrela have more antioxidants activity than Ceiba and crossopteryx , but fewer than ascorbic acid. Conclusion: The total polyphenol and others compounds in the leaves of Pseudocedrela may be used as natural antioxidants to prevent lead to oxidative stress lead.

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Published
2018-12-01
How to Cite
1.
Djadji A, Koua D, Sandrine S, Effo E, Kouakou L, Irie-N’GuessanG, Kouakou-Siransy GN. Total polyphenol content and antioxidants capacity of three Africans antipyretic plants. IJPR [Internet]. 1Dec.2018 [cited 18Mar.2019];8(11):122-6. Available from: https://ssjournals.com/index.php/ijpr/article/view/4977
Section
Research Articles

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