This study aimed to determine the Sero-prevalence of viral transfusion-transmissible Infectious diseases among blood donors, namely immunodeficiency virus, hepatitis B and C transmissible infections (TTIs like HBV, HCV.) HIV (Human immune viruses.). sero-prevalence of viral transmissible infections. The donated blood for specific antibodies for infections agents. Can largely reduce the risk of TTIs, virus among blood donors. The study was carried out in the blood bank at Khartoum Teaching Hospital, centre, Sudan. Screening of blood samples for hepatitis B surface Antigen (HBsAg), Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) Antibodies were done using (ELISA) enzyme link immunoassay. The study included (1184) voluntary Blood donors, all were males. The overall prevalence of viral transfusion transmissible Infections were (11.84%). The sero-prevalence for antibody against HIV (6) and hepatitis C Virus was positive in 8 (0.06) and (0.08%) donors respectively while HBsAg was detected in 98 (9.8%) donors. situation that need for strict criteria for selection of blood donors and also methods of laboratory assays. Services are high in Sudan due to the endemicity of infections like malaria, nutritional problem and obstetrical emergencies associated with blood loss. Little is known about the level of these infections in Sudan so; this study was conducted to investigate the sero-prevalence of transfusion transmissible viral infectious diseases in particular human B and hepatitis Immunodeficiency, hepatitis C viruses. The mode of transmission for HIV, HBV and HCV is the same and includes unsafe Sexual sharp materials Contact, using contaminated with body fluid, mother to Child and transfusion of blood and blood Products.
Liang TJ, Rehermann B, Seeff LB, Hoofnagle JH: Pathogenesis, natural history, treatment and prevention of hepatitis C. Annals of Internal Medicine 2000, 132:296-305.
Lok AS, McMahon BJ: Chronic hepatitis B. Hepatology 2001, 34:1225-1241.
Omer RE, Veer Van’t P, Kadaru AM, Kampman E, El Khidir IM, Fedail SS, Kok FJ: The role of hepatitis B and hepatitis C viral infections in incidence of hepatocellular carcinoma in Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene 2001, 95:487-491.
Brooks FG, Butel FJ, Morse AS: Hepatitis viruses. In Medical Microbiology. 22nd edition. Appleton and Lang, New York; 2001:403.
Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA: Hepatitis viruses. In Medical Microbiology. 4th edition. Mosby, St. Louis; 2002:591.
Bahatia R, Ichhpujani RI: Viral hepatitis. In Essentials of Medical Microbiology. 3rd edition. Jaypee Brothers, Medical Publishers, Ltd, New Delhi; 2004:396-406.
World Health Organization: Hepatitis B Surface Antigen Assays: Operational Characteristics. (Phase 1), (Report 2) 2004, 2.
Nagi AM, Altyeb HA, Ahmed AM: Seroprevalence of Hepatitis B and C Viral Infections among blood donors in Shendi, River Nile State, Sudan. Research Journal of Medicine and Medical Sciences 2007, 2(2):122-126.
Elsheikh RM, Daak AA, Elsheikh MA, Karsany MS, Adam I: Hepatitis B virus and hepatitis C virus in pregnant Sudanese women. Virology Journal 2007, 4:104.
McCarthy MC, El-Tigani A, Khalid IO, Hyams KC: Hepatitis B and C in Juba, southern Sudan: results of a serosurvey. Transactions of Royal Society of Tropical Medicine and Hygiene 1994, 88:534-536.
Mudawi HMY, Smith HM, Rahoud SA, Fletcher IA, Babikir AM, Saeed OK, Fedail SS: Epidemiology of HCV Infection in Gezira State of Central Sudan. Journal of Medical Virology 2007, 79:383-385.
Scott J, McMahon B, Bruden D, Sullivan D, Homan C, Christensen C, Gretch D: High rate of spontaneous negativity for hepatitis C virus RNA after establishment of chronic infection in Alaska Natives.
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