Subtractive genomics, Therapeutic drug target, Unique pathways, Homologs
Introduction: Antibacterial agents are one of the most frequently used drugs word wide, and contribute immensely to human health system. Maternal health is very important because both fetus and mother are at jeopardy. Many drugs are used in Obstetrics and Gynecology department but they are least studied with respect to drug utilization which is a potential tool in evaluation of health systems. Thus, present study was undertaken to analyze drug utilization pattern of Obstetrics and Gynecology Department in a tertiary care hospital. Methods: This prospective study of the audit prescription was conducted for a period of three months from March 2016 to May 2016 on patients visiting the Obstetrics and Gynecology department during the study period. Patients were enrolled on the basis of inclusion and exclusion criteria. Results 130 patients were analyzed. Antibiotics were prescribed for eclampsia followed by full term pregnancy (FTP) in labor, puerperal sepsis, intra-uterine death with previous LSCS with diabetes and pregnancy induced hypertension. ?-lactams were most commonly prescribed antimicrobials to 47.46% of patients, other drugs that were commonly prescribed were proton-pump inhibitors and NSAIDs. Out of 433 drugs which were prescribed to 130 patients, 316 were antibiotics. The average numbers of antibacterial agents which were prescribed per patients per course was found to be 3.88 and average cost per prescription per day was Rs.210.50 and the average antibiotic cost per encounter was Rs.168.50. Conclusion: Our study demonstrated that most of the prescription were found to be rational according to the use of AMAs which helps in reducing adverse events and health care cost.
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